Table 3.
Comparison of the characteristics of the patients with aneurysms who were aged ≤ 60 and > 60 years
| ≤60 years (n = 273) | >60 years (n = 130) | P value | |
|---|---|---|---|
| Age (year) | 52.6 ± 5.8 | 66.8 ± 4.6 | |
| Female sex | 118 (43.2) | 75 (57.7) | 0.007 |
| Multiple aneurysms | 16 (5.9) | 16 (12.3) | 0.025 |
| Posterior circulation | 17 (6.2) | 2 (1.5) | 0.014 |
| Hypertension | 86 (31.5) | 76 (58.5) | < 0.001 |
| CAD | 20 (7.3) | 24 (18.5) | 0.001 |
| Diabetes mellitus | 25 (9.2) | 28 (21.5) | 0.001 |
| Smoking | 79 (28.9) | 9 (6.9) | < 0.001 |
| Alcohol drinking | 155 (56.8) | 47 (36.2) | < 0.001 |
| F/Hx of hypertension | 129 (47.3) | 51 (39.2) | 0.130 |
| F/Hx of CAD | 44 (16.1) | 11 (8.5) | 0.036 |
| F/Hx of stroke | 92 (33.7) | 40 (30.8) | 0.558 |
| BMI | 24.0 ± 3.1 | 24.1 ± 2.8 | 0.718 |
| Hb | 14.4 ± 1.4 | 13.8 ± 1.5 | < 0.001 |
| Hct | 42.6 ± 3.6 | 41.2 ± 4.0 | < 0.001 |
| ESR | 11.6 ± 9.2 | 17.4 ± 12.7 | < 0.001 |
| hS-CRP | 0.1 ± 0.2 | 0.1 ± 0.1 | 0.259 |
| PT INR | 1.0 ± 0.1 | 1.0 ± 0.1 | 0.044 |
| aPTT | 28.0 ± 2.0 | 27.6 ± 1.8 | 0.065 |
| Albumin | 4.2 ± 0.3 | 4.1 ± 0.3 | 0.039 |
| Na | 142.2 ± 2.2 | 142.7 ± 2.1 | 0.072 |
| K | 4.1 ± 0.3 | 4.1 ± 0.4 | 0.606 |
| BUN | 13.0 ± 3.4 | 14.5 ± 4.5 | < 0.001 |
| Cr | 0.8 ± 0.2 | 0.9 ± 0.4 | 0.276 |
| HbA1c | 5.6 ± 0.6 | 5.9 ± 0.9 | 0.002 |
| TC | 190.3 ± 34.3 | 185.6 ± 36.8 | 0.213 |
| TG | 123.5 ± 73.5 | 112.9 ± 53.5 | 0.100 |
| HDL | 54.6 ± 15.9 | 54.3 ± 13.9 | 0.823 |
| LDL | 119.4 ± 30.3 | 116.7 ± 32.5 | 0.416 |
| TSH | 3.1 ± 2.8 | 2.8 ± 1.9 | 0.385 |
| fT4 | 1.3 ± 0.2 | 1.3 ± 0.2 | 0.021 |
| Uric acid | 5.2 ± 1.4 | 5.2 ± 1.4 | 0.866 |
| Aneurysm characteristics | |||
| Size of aneurysm | 3.9 ± 1.4 | 4.5 ± 2.2 | 0.001 |
| ASPECT ratio | 1.5 ± 0.7 | 1.4 ± 0.7 | 0.393 |
| Dome/neck ratio | 1.6 ± 0.6 | 1.5 ± 0.6 | 0.423 |
| Location of aneurysm | |||
| ICA (n = 178) | 119 (43.6) | 59 (45.4) | 0.439 |
| MCA (M1 and M2) (n = 27) | 17 (6.2) | 10 (7.7) | |
| MCA bifurcation (n = 54) | 34 (12.5) | 20 (15.4) | |
| ACA (n = 28) | 19 (7.0) | 9 (6.9) | |
| Acom (n = 55) | 36 (13.2) | 19 (14.6) | |
| Pcom (n = 42) | 31 (11.4) | 11 (8.5) | |
| Posterior circulation (n = 19) | 17 (6.2) | 2 (1.5) | |
Values are presented as the number of patients (%) or means (SDs). P values were calculated using Pearson χ2 test or Student’s t-test, as appropriate
ACA anterior cerebral artery, Acom anterior communicating artery, BMI body mass index, CAD coronary artery disease, CRP C-reactive protein, ESR erythrocyte sedimentation rate, F/Hx family history, Hb hemoglobin, Hct hematocrit, HDL high-density lipoprotein, ICA internal carotid artery, LDL low-density lipoprotein, MCA middle cerebral artery, Pcom posterior communicating artery, TC total cholesterol, TG triglyceride, TSH thyroid-stimulating hormone
P value of < 0.05 was considered statistically significant