Table 4.
Potential and known risk factors for cancer after pediatric solid organ transplantation with univariate and multivariate Cox proportional-hazards models
| Univariate | Multivariate | |||
|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |
| Organ | ||||
| Kidney | Ref. | Ref. | ||
| Liver | 0.50 | 0.11, 2.19 | 0.50 | 0.11, 2.24 |
| Heart | 0.63 | 0.14, 2.79 | 0.63 | 0.14, 2.87 |
| Tx age (years) | ||||
| 0–4.99 | Ref. | Ref. | ||
| 5–9.99 | 0.99 | 0.27, 3.68 | 0.94 | 0.25, 3.55 |
| 10–15.99 | 0.86 | 0.30, 2.43 | 0.83 | 0.27, 2.55 |
| Tx year | ||||
| 1982–1993 | Ref. | Ref. | ||
| 1994–2003 | 1.26 | 0.47, 3.36 | 1.27 | 0.46, 3.49 |
| 2004–2015 | 1.38 | 0.16, 12.2 | 1.56 | 0.16, 15.9 |
| Sex | ||||
| Male | Ref. | Ref. | ||
| Female | 0.98 | 0.27, 3.68 | 0.92 | 0.35, 2.42 |
For categorical variables, the reference category is marked with “Ref.”
HR hazard ratio, 95% CI 95% confidence interval, Tx transplant