Table 2.
Serogroups and toxins as risk factors for HUS in 256 STEC positive patients using binary logistic regression model
HUS (56) | STEC without HUS (200) | OR (95% CI) | p value | Adjusted OR* | p value | |
---|---|---|---|---|---|---|
Serogroup O157 | 37 (66%) | 103 (52%) | 1.83 (0.99–3.41) | NS | 2.14 (1.11–4.12) | 0.02 |
Serogroup O26 | 6 (11%) | 20 (10%) | 1.08 (0.41–2.83) | NS | 1.12. (0.41–3.19) | NS |
Serogroup O121 | 4 (7%) | 4 (2%) | 3.77 (0.91–15.58) | NS | 2.66 (0.61–11.60) | NS |
Stx1(with or without Stx2) | 5 (9%) | 118 (59%) | 0.07(0.03–0.19) | < 0.001 | 0.07 (0.03–0.18) | < 0.001 |
Stx1 alone | 2 (4%) | 54 (27%) | 0.10 (0.02–0.43) | 0.002 | 0.09 (0.02–0.39 | 0.001 |
Stx1a | 4 (7%) | 108 (54%) | 0.07 (0.03–0.19) | < 0.001 | 0.07 (0.02–0.19) | < 0.001 |
Stx2 (with or without Stx1) | 54 (96%) | 147 (74%) | 9.74 (2.29–41.33) | 0.002 | 11.03 (2.56–47.53) | 0.001 |
Stx2 alone | 51 (91%) | 82 (41%) | 14.68 (5.62–38.36) | < 0.001 | 14.84 (5.62–39.20) | < 0.001 |
Stx2a | 51 (91%) | 76 (38%) | 16.64 (6.36–43.54) | < 0.001 | 17.41 (6.55–46.27) | < 0.001 |
Stx2c | 1 (2%) | 56 (28%) | 0.05 (0.01–0.35) | 0.003 | 0.47 (0.06–4.00) | NS |
Stx1 and Stx2 | 3 (5%) | 65 (33%) | 0.12 (0.04–0.39) | < 0.001 | 0.12 (0.04–0.42) | 0.001 |
eae | 52 (93%) | 172 (86%) | 2.12 (0.71–6.31) | NS | 1.92 (0.63–5.81) | NS |
CI confidence interval, NS nonspecific, OR odds ratio, aOR adjusted odds ratio with confidence intervals for age groups < 3 and ≥ 3 years and sex