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. 2020 Apr 22;35(9):1749–1759. doi: 10.1007/s00467-020-04560-0

Table 2.

Serogroups and toxins as risk factors for HUS in 256 STEC positive patients using binary logistic regression model

HUS (56) STEC without HUS (200) OR (95% CI) p value Adjusted OR* p value
Serogroup O157 37 (66%) 103 (52%) 1.83 (0.99–3.41) NS 2.14 (1.11–4.12) 0.02
Serogroup O26 6 (11%) 20 (10%) 1.08 (0.41–2.83) NS 1.12. (0.41–3.19) NS
Serogroup O121 4 (7%) 4 (2%) 3.77 (0.91–15.58) NS 2.66 (0.61–11.60) NS
Stx1(with or without Stx2) 5 (9%) 118 (59%) 0.07(0.03–0.19) < 0.001 0.07 (0.03–0.18) < 0.001
Stx1 alone 2 (4%) 54 (27%) 0.10 (0.02–0.43) 0.002 0.09 (0.02–0.39 0.001
Stx1a 4 (7%) 108 (54%) 0.07 (0.03–0.19) < 0.001 0.07 (0.02–0.19) < 0.001
Stx2 (with or without Stx1) 54 (96%) 147 (74%) 9.74 (2.29–41.33) 0.002 11.03 (2.56–47.53) 0.001
Stx2 alone 51 (91%) 82 (41%) 14.68 (5.62–38.36) < 0.001 14.84 (5.62–39.20) < 0.001
Stx2a 51 (91%) 76 (38%) 16.64 (6.36–43.54) < 0.001 17.41 (6.55–46.27) < 0.001
Stx2c 1 (2%) 56 (28%) 0.05 (0.01–0.35) 0.003 0.47 (0.06–4.00) NS
Stx1 and Stx2 3 (5%) 65 (33%) 0.12 (0.04–0.39) < 0.001 0.12 (0.04–0.42) 0.001
eae 52 (93%) 172 (86%) 2.12 (0.71–6.31) NS 1.92 (0.63–5.81) NS

CI confidence interval, NS nonspecific, OR odds ratio, aOR adjusted odds ratio with confidence intervals for age groups < 3 and ≥ 3 years and sex