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. 2020 Jul 27;10:12500. doi: 10.1038/s41598-020-68860-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Malodour producing staphylococci contain a unique C-S lyase enzyme. Maximum likelihood tree of PLP dependent C-S lyases from representative bacterial species. A unique PLP dependent PatB enzyme is found in a distinct phylogenetic clade of staphylococcal species, which we refer to as malodour producing staphylococci (coloured orange, G1). Coloured dots represent selected PLP-dependent enzymes purified for further biochemical characterisation. Orthologous PatB enzymes found in other Staphylococcusal spp. are indicated by G1, G2 and G3. Phylogenetic tree was generated using iTOL (https://itol.embl.de/).