Table 3.
Meta-analysis of clinical manifestations.
| Pooled frequency | n/N* | Publication bias | Heterogeneity test | ||
|---|---|---|---|---|---|
| (95% CI) | (p-value) | I2 (%) | p-value | ||
| Fever | 83.0 (77.5–87.6) | 2,073/2,465 | 0.76 | 86 | 0.00 |
| Cough | 65.2 (58.6–71.2) | 1,689/2,515 | 0.80 | 85 | 0.00 |
| Dyspnea | 27.4 (19.6–35.2) | 477/2,014 | 0.42 | 89 | 0.00 |
| Myalgia/fatigue | 34.7 (26.0–44.4) | 742/1,938 | 0.60 | 89 | 0.00 |
| Sputum production | 17.2 (10.8–26.4) | 480/1,862 | 0.01 | 89 | 0.00 |
| Sore throat | 14.5 (10.6–19.5) | 224/1,577 | 0.88 | 66 | 0.00 |
| Headache | 11.1 (7.7–15.7) | 230/1,864 | 0.30 | 74 | 0.00 |
| Diarrhea | 5.7 (3.8–8.6) | 104/2,041 | 0.77 | 66 | 0.00 |
| Hemoptysis | 2.4 (0.8–6.7) | 20/1,339 | 0.77 | 100 | 0.00 |
| Anorexia | 10.1 (1.0–57.2) | 82/1,322 | 0.73 | 98 | 0.00 |
| Nausea/vomiting | 5.0 (2.3–10.7) | 65/1,563 | 0.90 | 85 | 0.00 |
| Dizziness | 8.6 (2.5–26.0) | 16/205 | 0.90 | 65 | 0.00 |
| Chest tightness | 8.4 (2.5–26.0) | 24/256 | 0.24 | 78 | 0.00 |
| Rhinorrhea | 9.3 (2.2–31.0) | 28/232 | 0.17 | 88 | 0.00 |
| Chills | 14.3 (3.0–47.4) | 12/111 | NA | 86 | 0.00 |