Table 6.
Subgroup analysis for serum and plasma levels of inteleukin-6 in adults where mean BMI of OSAS patients ≤ 30 kg/m2.
| Subgroup analysis of serum level (n) | MD (95% CI), P-value, I2 (%), Ph | Subgroup analysis of plasma level (n) | MD (95% CI), P-value, I2 (%), Ph |
|---|---|---|---|
| Overall (19) | 10.59 (8.64, 12.53), <0.00001, 100, <0.00001 | Overall (11) | 4.20 (2.95, 5.46), <0.00001, 99, <0.00001 |
| Mean BMI of controls, kg/m2 | Mean BMI of controls, kg/m2 | ||
| >30 (1) | 4.03 (2.38, 5.68), <0.00001 | >30 (0) | NA |
| ≤ 30 (18) | 11.02 (9.01, 13.04), <0.00001, 100, <0.00001 | ≤ 30 (11) | 4.10 (2.86, 5.34), <0.00001, 99, <0.00001 |
| Total number of participants | Total number of participants | ||
| >100 (7) | 11.92 (2.31, 21.52), 0.02, 100, <0.00001 | >100 (3) | 0.49 (−0.08, 1.06), 0.09, 96, <0.00001 |
| ≤ 100 (12) | 8.59 (6.89, 10.29), <0.00001, 99, <0.00001 | ≤ 100 (8) | 7.06 (3.68, 10.44), <0.0001, 99, <0.00001 |
| Mean AHI of OSAS patients, events/h | Mean AHI of OSAS patients, events/h | ||
| >30 (7) | 18.16 (10.17, 26.15), <0.00001, 100, <0.00001 | >30 (6) | 8.48 (4.75, 12.21), <0.00001, 99, <0.00001 |
| ≤ 30 (2) | 1.05 (−0.16, 2.27), 0.09, 71, 0.06 | ≤ 30 (4) | 0.16 (−0.16, 0.48), 0.32, 68, 0.02 |
BMI, body mass index; CI, confidence interval; OSAS, obstructive sleep apnea syndrome; MD, mean difference; NA, not available; Ph, Pheterogeneity.
Bold numbers for statistically significant values (P < 0.05).