Table 3.
SKAT-O on genes results (top 10 genes).
| EP | PPMI | |||
|---|---|---|---|---|
| Gene | tested variants | p-value | tested variants | p-value |
| ANAPC5 | 3 (0) | 0.0005 | 6 (2) | NS |
| PDE2A | 2 (0) | 0.0009 | 10 (2) | NS |
| FANCA | 4 (1) | 0.0009 | 0 | NA |
| SGK494 | 2 (0) | 0.0013 | 6 (2) | NS |
| DOCK4 | 9 (4) | 0.0016 | NA | NA |
| APOL5 | 2 (0) | 0.0018 | 4 (1) | NS |
| RasGRF2 | 2 (1) | 0.0019 | NA | NA |
| ITGA6 | 3 (0) | 0.0019 | 18 (1) | NS |
| ITGA11 | 7 (4) | 0.0020 | 21 (4) | NS |
| MYH14 | 7 (4) | 0.0031 | 26 (3) | NS |
Tested variants are reported as number of tested variants (number of unique variants, i.e., found only once in the cohort).