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. 2020 Jul 21;7:148. doi: 10.3389/fmolb.2020.00148

TABLE 2.

Univariate Cox analysis and Multivariate Cox analysis of BTLA expression and other clinicopathological factors.

Variable Univariate Cox Regression
Multivariate Cox Regression
β HR (95% CI) Z score p β HR (95% CI) Z score p
Age: ≥60 vs <60 0.52 1.7 (1.0–2.8) 4.0 0.045** 0.70 2.0 (1.2–3.4) 2.6 0.0089**
Gender: Female vs male 0.14 1.1 (0.77–1.7) 0.45 0.50
Disease stage: high vs low 0.83 2.3 (1.8–2.9) 51 1.10E-12*** 0.064 1.1 (0.56–2.0) 0.19 0.85
T stage: high vs low 1.1 3 (2.0–4.4) 28 1.40E-07*** 0.75 2.1 (1.3–3.4) 3.2 0.0013**
N stage: high vs low 0.76 2.1 (1.7–2.7) 42 1.10E-10*** 0.51 1.7 (1.1–2.5) 2.5 0.011*
M stage: high vs low 1.5 4.3 (2.8–6.6) 47 8.40E-12*** 0.75 2.1 (0.86–5.2) 1.6 0.10
BTLA expression: high vs low −0.77 0.46 (0.31–0.70) 13 0.00027*** −0.62 0.54 (0.35–0.82) −2.9 0.0037**

*p < 0.05; **p < 0.01; ***p < 0.001.