Table 3.
Stability of Koumine (KM) in rat plasma under different conditions (n = 3).
| Spiked Concentration (ng·ml−1) | 3 Freeze-thaw cycles | Short-term storage | Long-term storage | Post-preparative |
|---|---|---|---|---|
| RE (%) | RE (%) | RE (%) | RE (%) | |
| 0.2 | −4.2 | 1.3 | 3.3 | −1.6 |
| 0.6 | 3.3 | −1.7 | 11.0 | 0.4 |
| 10 | −11.7 | −13.7 | −5.8 | 9.6 |
| 150 | −9.6 | −9.3 | −6.0 | −4.5 |
| IS | −3.1 | 1.9 | −11.7 | 5.4 |