TABLE 3.
Significantly changed genes and KEGG pathways involved in metabolism response in the hepatopancreas of Chinese mitten crab under pH 9.5 vs in the control group for 8 weeks.
| Pathway term | Associated genes | P-value |
| Starch and sucrose metabolism | MGAM| E3.2.1.1, amyA, malS| E3.2.1.28, treA, treF| SI| | PTS-Glc-EIIA, crr| GPI, pgi| TPS | 1.75 E-04 |
| Glycolysis/gluconeogenesis | ENO, eno| E4.1.1.32, pckA, PEPCK| GAPDH, gapA| ADPGK| FBA, fbaA| LDH, ldh| PTS-Glc-EIIA, crr| PGK, pgk| GPI, pgi| GAPDH, gapA| gpmI | 8.07 E-04 |
| One carbon pool by folate | FTCD| MTHFS| metF, MTHFR | 0.010 |
| Amino sugar and nucleotide sugar metabolism | nagA, AMDHD2| PTS-Nag-EIIC, nagE| PTS-Glc-EIIA, crr| GPI, pgi| manA, MPI | 0.010 |
| Linoleic acid metabolism | PLA2G, SPLA2| CYP2J| CYP3A | 0.015 |
| Galactose metabolism | MGAM| SI | 0.025 |
| Glycosaminoglycan degradation | NAGLU| SGSH | 0.043 |
| Taurine and hypotaurine metabolism | CSAD | 0.048 |