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. 2020 Jun 10;111(7):2310–2324. doi: 10.1111/cas.14444

Figure 1.

Figure 1

ETS homologous factor is upregulated in CRC and positively associated with poor prognosis in CRC patients. A, B, Expression levels of EHF mRNA (A) and protein (B) in CRC and colon mucosa epithelial (FHC) cell lines. C, D, Expression levels of EHF mRNA (C) and protein (D) in paired CRC and adjacent noncancerous tissues. E, Analysis of EHF expression in colon and rectum adenocarcinoma compared with in normal mucosa according to TCGA and GTEx databases. F, Expression analysis of EHF protein in CRC and normal colorectal mucosa tissues by IHC. Scale bars, 50 μm (×200 magnification) or 20 μm (×400 magnification). G, Correlation between EHF expression and overall survival in CRC patients. The median value of EHF expression was chosen as the point for separating tumors into low‐level and high‐level expression groups (log‐rank P = .0006)