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SMPDL3B knockdown (KD) significantly inhibits tumor growth. A, Nude mice with tumors were imaged; tumors are marked with a circle. B, Tumor tissues were collected and imaged. C, The weight of mouse (left), weight (middle) and the size (right) of the tumor and were collected and analyzed. D, The protein levels of SMPDL3B in tumor tissues were investigated by western blot; representative results are shown. Data were analyzed using Student t test (*P < .05; **P < .01)
