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. 2020 Jul 7;111(7):2488–2498. doi: 10.1111/cas.14489

Table 6.

Concordance with TTF‐1 and p40 immunostaining and PD‐L1 expression evaluation

Concordance with immunostaining
NSCLC (N = 62) Cryoprobe
Positive Negative Total
TTF‐1
Forceps
Positive 29 0 29
Negative 1 32 33
Total 30 32 62
Concordance rate = 98%
p40
Forceps
Positive 24 1 24
Negative 1 37 38
Total 25 37 62
Concordance rate = 97%
PD‐L1 expression
NSCLC (N = 62) Evaluable Unevaluable Total, n (%)
Forceps
Evaluable 59 2 61 (98)
Unevaluable 1 0 1 (2)
Total, n (%) 60 (97) 2 (3) P = 0.56
Evaluable (N = 59) ≥1% <1% Total, n (%)
Forceps
≥1% 24 1 25 (42)
<1% 6 28 34 (58)
Total, n (%) 30 (51) 8 (49) P = 0.06
Evaluable (N = 59) ≥50% <50% Total, n (%)
Forceps
≥50% 8 1 9 (15)
<50% 4 46 50 (85)
Total, n (%) 12 (20) 47 (80) P = 0.18

Abbreviations: NSCLC, non–small cell lung cancer; PD‐L1, programmed death ligand 1; TTF‐1, thyroid transcription factor 1.