Table 4.

Prognostic factors affecting the progression‐free survival of patients with diffuse large B‐cell lymphoma

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Lymph2Cx ABC (vs GCB, unclassified)	1.61 (0.87‐3.00)	0.13	1.09 (0.44‐2.64)	0.85
IPI high (3‐5) (vs low [0‐2])	2.26 (1.17‐4.53)	0.02	2.19 (1.04‐4.69)	0.04
MYC translocation positive (vs negative)	2.60 (0.89‐6.10)	0.08	1.27 (0.28‐4.12)	0.72
DEL (vs non‐DEL)	1.84 (0.93‐3.47)	0.08	1.55 (0.64‐3.80)	0.33
CD47high/SIRPαhigh (vs others†)	2.46 (1.29‐4.68)	0.007	2.87 (1.42‐5.85)	0.003

Abbreviations: ABC, activated B‐cell; CI, confidence interval; DEL, double expressor lymphoma; GCB, germinal center B‐cell; IPI, international prognostic index.

†Including CD47^high/signal‐regulatory protein‐α (SIRPα)^low, CD47^low/SIRPα^high, and CD47^low/SIRPα^low.