Table 2.
Univariate and multivariate analysis of OS in CGGA sequencing database
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P‐value | HR (95% CI) | P‐value | |
| Risk score | 4.804 (3.734‐6.181) | <.001 | 4.190 (2.576‐6.816) | <.001 |
| Age at diagnosis | 1.038 (1.023‐1.054) | <.001 | 0.995 (0.975‐1.016) | .660 |
| Gender | 1.181 (0.837‐1.666) | .345 | ‐ | ‐ |
| WHO grade | 3.477 (2.716‐4.452) | <.001 | 1.716 (1.141‐2.582) | .010 |
| TCGA subtype | 1.935 (1.641‐2.282) | <.001 | 0.831 (0.619‐1.115) | .217 |
| IDH mutation status | 0.228 (0.158‐0.329) | <.001 | 1.083 (0.522‐2.250) | .830 |
| MGMT methylation | 0.528 (0.374‐0.450) | <.001 | 0.721 (0.461‐1.128) | .152 |
| 1p19q codeletion | 0.134 (0.049‐0.363) | <.001 | 0.712 (0.243‐2.085) | .536 |
| Radiotherapy | 0.429 (0.296‐0.622) | <.001 | 0.446 (0.286‐0.695) | <.001 |
| Chemotherapy | 1.378 (0.963‐1.971) | .079 | ‐ | ‐ |