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SLC12A5 regulates the expression of SOX18 target gene MMP7 in BUC cells. A, SOX18 luciferase reporter activities were analyzed in the indicated cells. Each bar represents the mean ± SD of 3 independent experiments. B, ChIP assay using anti‐SOX18 antibodies to test the enrichment at the MMP7 promoter. C, MMP7 mRNA level was examined in BUC cells with SLC12A5 overexpression or knockdown. D, Protein level of MMP7 was examined in cells with SLC12A5 overexpression or knockdown; **P < .01
