Figure 2.

Rv1507A induces enhanced generation of lymphoid subpopulations. BALB/c mice (n = 6) were injected with Ms_Vc (1 × 10⁷) or Ms_Rv1507A (1 × 10⁷). Primed splenocytes obtained from mice were cultured in-vitro in presence of Rv1507A. The generation of CD3⁺ T cells, CD19⁺ B cells, and F4/80 macrophage cells, were measured by flow cytometry (A,B). Note the increased generation of CD19⁺ B cells, CD3⁺ T cells, and F4/80⁺ macrophage cells. Expression of CD80, CD86, MHCII, CD40, and CD69 on primed splenocytes (A,C) are shown in MFI as mean ± SEM. p < 0.05 was considered significant, **p < 0.01.