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. 2020 Jul 28;268(3):743–750. doi: 10.1007/s00415-020-10099-9

Table 2.

Behavioral and quality of life assessment pre- and during the COVID-19 lockdown in Italy

T0 T1 T p
BDI-II—mean (SD) 9.94 (7.9) 8.6 (9.3) 1.589 .117
STAI-Y1—mean (SD) 42.1 (11.4) 43.5 (12) – 1.005 .319
MSQoL physical health—mean (SD) 78.5 (26.9) 82.6 (24.4) – 1.716 .091
MSQoL limitations due to physical problems—mean (SD) 77.4 (35.2) 77.3 (35.2) .015 .988
MSQoL limitations due to emotional problems—mean (SD) 81.5 (32.7) 67.7 (40.7) 3.102 .003
MSQoL pain—mean (SD) 75.4 (25.3) 82 (25) – 1.876 .065
MSQoL emotional well-being—mean (SD) 64.2 (18.4) 64.3 (21.4) – .059 .954
MSQoL energy—mean (SD) 51.1 (18.2) 48.1 (17.9) 1.518 .134
MSQoL health perceptions—mean (SD) 54.4 (20.9) 55.9 (21.4) – .705 .483
MSQoL social function—mean (SD) 77.7 (17.4) 84.2 (20.4) – 3.133 .003
MSQoL cognitive function—mean (SD) 72.7 (18.2) 74.3 (23.6) – .742 .461
MSQoL health distress—mean (SD) 72.9 (22.4) 74.2 (23.9) – .621 .537
MSQoL sexual function—mean (SD) 83.3 (26) 87.2 (21.8) – 1.066 .290
MSQoL change in health—mean (SD) 44.9 (22.3) 53.5 (21.8) – 2.295 .025
MSQoL satisfaction with sexual function—mean (SD) 70.1 (25.7) 89.3 (21.1) – 5.791  < .001
MSQoL overall quality of life—mean (SD) 64.2 (21.3) 68.4 (16.3) – 1.702 .094
MSQoL physical health composite score—mean (SD) 70.2 (17.8) 72.9 (19.8) – 1.487 .142
MSQoL mental health composite score—mean (SD) 71.1 (17.7) 68.7 (21.8) 1.278 .206

Values at T0 and T1 are expressed as mean (standard deviation). T0 before the lockdown, T1 during the lockdown, t paired sample t test, p probability value, BDI-II Beck Depression Inventory, second edition, STAI-State State Anxiety section of the State-Trait Anxiety Inventory (STAI-Y-1), MSQoL-54 Multiple Sclerosis Quality of Life-54. Significant values (p < .05) are reported in bold. Significant values after Benjamini–Hochberg procedure are underlined