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[Preprint]. 2020 Jul 16:3652322. [Version 1] doi: 10.2139/ssrn.3652322

Figure 4. TH1 cells are prominent among CD4+T cell subsets in thoracic lymph nodes and spleens.

Figure 4.

(A) Representative multi-color staining showing TH1, TH2, TH17 and Treg cells in lymph nodes form early (left) and late (middle) COVID-19 patients and control (right). [TH1: CD4+ (red) T-bet+ (light blue)] [TH2: CD4+ (red) GATA3+ (purple)] [TH17: CD4+ (red) RORγ+ (yellow)] [Treg: CD4+ (red) FoxP3+ (green)]. (B) Relative proportions of TH1 (upper left), TH2 (upper right), TH17 (lower left) and Treg (lower right) cells among CD4+ T cells in lymph nodes and spleens from early (purple) (n = 5) and late (blue) (n = 6) COVID-19 patients and controls (green) (n = 10). Multiple comparisons are controlled for by Kruskal-Wallis test. Error bars represent mean ±SEM. *p < 0.05; **p < 0.01.