Figure 1.

Benign prostatic hyperplasia (BPH) in human prostate tissue. (A) Diagrams representing anatomical features of normal human prostate and BPH. BPH originates within the preprostatic region, containing the transition zone (TZ) and periurethral glands. A dashed line through the BPH diagram represents an approximate cross-sectional location of a whole-mount pathological view of BPH, as in (B) and (C). Human prostate cut along the transverse plan to observe a gross view (B) or whole mount H&E section (C). TZ and peripheral zone (PZ) are labeled and BPH nodules are indicated by black arrows. Modified from Aaron et al. [8].