Table 3.
Multivariable Cox proportional hazard regression analyses.
| characteristics | OS |
CSS |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
| Year of surgery | ||||||
| 2007–2010 | Reference | |||||
| 2011–2013 | 1.03 | 0.88–1.21 | 0.703 | 1.01 | 0.85–1.16 | 0.889 |
| 2014–2016 | 0.93 | 0.76–1.08 | 0.232 | 0.96 | 0.81–1.15 | 0.686 |
| Age, year | 1.03 | 1.02–1.04 | <0.001 | 1.03 | 1.01–1.04 | <0.001 |
| Gender | ||||||
| Male | Reference | |||||
| Female | 1.15 | 0.85–1.55 | 0.498 | 1.18 | 0.84–1.66 | 0.342 |
| BMI kg/m2 | 0.96 | 0.93–1.00 | 0.071 | 0.99 | 0.95–1.04 | 0.802 |
| ASA group | ||||||
| Ⅰ+Ⅱ | Reference | |||||
| Ⅲ+Ⅳ | 1.28 | 1.03–1.60 | 0.028 | 1.22 | 0.95–1.57 | 0.115 |
| Surgical approach | ||||||
| Open | Reference | |||||
| Minimally invasive | 0.95 | 0.77–1.17 | 0.653 | 0.97 | 0.77–1.23 | 0.816 |
| Pathologic stage | ||||||
| ≤T2 | Reference | |||||
| ≥T3 | 1.84 | 1.46–2.31 | <0.001 | 2.41 | 1.86–3.13 | <0.001 |
| Pathologic grade | ||||||
| LG | Reference | |||||
| HG | 1.26 | 0.88–1.80 | 0.209 | 1.07 | 0.72–1.59 | 0.749 |
| Pathological nodal involvement | ||||||
| No | Reference | |||||
| Yes | 2.46 | 1.93–3.13 | <0.001 | 2.62 | 2.00–3.42 | <0.001 |
| Positive surgical margin | ||||||
| No | Reference | |||||
| Yes | 1.71 | 1.19–2.46 | 0.004 | 1.78 | 1.19–2.66 | 0.005 |
| PLND | ||||||
| Standard PLND | Reference | |||||
| Extensive PLND | 1.26 | 0.93–1.72 | 0.135 | 1.30 | 0.92–1.83 | 0.139 |
BMI, body mass index; OS, overall survival; CSS, cancer-specific survival; HR, hazard ratio; CI, confidence interval; ASA, the American Society of Anesthesiologists; PLND, pelvic lymph node dissection.