Table 1.

Clonality analysis and IDH1/2 Mutation analysis of dedifferentiated chondrosarcoma specimens.

Case	Age (y)	Sex	Site	Follow-up (months)	Clonality	IDH1 mutation		IDH2 mutation
						C-DDCS	D-DDCS	C-DDCS	D-DDCS
1	44	F	Femur	DOD8m	Monoclonal	R132C	R132C	WT	WT
2	62	F	Femur	DOD7m	Failed	WT	WT	WT	WT
3	39	F	Pelvis	DOD10m	Monoclonal	R132S	R132S	R159H	R159H
4	42	F	Pelvis	DOD32m	Failed	R132C	R132C	WT	WT
5	48	F	Pelvis	DOD5m	Uninformative	WT	WT	WT	WT
6	49	F	tibia	AWD74m	Monoclonal	WT	WT	WT	WT
7	46	F	Humerus	DOD72m	Failed	WT	WT	WT	WT
8	62	F	Pelvis	AWD6m	Monoclonal	R132S	R132S	WT	WT
9	45	F	Humerus	AWD36m	Failed	WT	WT	WT	WT
10	51	M	T8-12	DOD7m	Not tested	WT	WT	WT	WT
11	44	M	sternum	DOD27m	Not tested	R132F	R132F	WT	WT
12	50	M	Pelvis	DOD5m	Not tested	R132H	R132H	WT	WT
13	72	M	Femur	DOD17m	Not tested	R132G	R132G	WT	WT
14	53	M	Pelvis	DOD5m	Not tested	R132G	R132G	WT	WT
15	45	M	Pelvis	DOD9m	Not tested	R132G	R132G	WT	WT
16	58	M	Pelvis	DOD2m	Not tested	WT	WT	WT	WT
17	33	M	finger	AWD19m	Not tested	R132C	R132C	WT	WT
18	69	M	Femur	AWD11m	Not tested	WT	WT	R172S	R172S

Abbreviations: F, female; M, male; DOD, died of disease; AWD, alive with disease; m, months; C-DDCS, chondrosarcoma component of DDCS; D-DDCS, dedifferentiated component of DDCS; WT, wild type.