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. 2020 Jul 27;10:12457. doi: 10.1038/s41598-020-69326-y

Table 1.

Observed distribution of genotypes for ABCB1.

Abbreviated description of SNP combination group Number of subjects Combinations of variants
Trial I Trial II
CGC/CGCa 3 6 1236 C/C + 2677 G/G + 3435 C/C
CGC/CGTa,b 2 3 1236 C/C + 2677 G/G + 3435 C/T
CGC/TTTa 8 7 1236 C/T + 2677 G/T + 3435 C/T
TTT/TTTa 3 6 1236 T/T + 2677 T/T + 3435 T/T
1 1236 C/T + 2677 G/T + 3435 T/T
1 1236 C/C + 2677 G/T + 3435 T/T

a38 out of forty subjects in the two trials were included in our evaluation of the effect of SNP combinations. P-gp, P-glycoprotein.

bContains one non-compliant subject.