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. 2020 Jul 27;11:3748. doi: 10.1038/s41467-020-17505-w

Fig. 2. The major capsid and auxiliary proteins.

Fig. 2

a Cartoon representation of the major capsid protein with blue–red gradient from N- to C-terminus. b The auxiliary protein is a homotrimer composed of two domains with a β-tulip fold and an N-terminal hook. c Wall-eyed stereo image of the homologous λ cementing protein, gpD (PDB ID 1C5E, orange) aligned with YSD1_16 (blue). Arrows highlight the two main differences in the N-terminal region and β-tulip domain. d, e Cartoon representations of the major capsid protein structures (grey) derived from a crystal structure of the monomeric protein (RX, d) and the cryo-EM reconstruction (e). Conformational switches of the E-loop, N-ter and A-domain regions are highlighted by arrows. f Hexon capsomer in the cryo-EM structure of the icosahedral head.