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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Anesth Analg. 2019 Nov;129(5):1273–1280. doi: 10.1213/ANE.0000000000003572

Table 2.

Effect of hypoxia and cyanide on hemodynamics. 20 independent measurements (one for each rat) were taken for every variable.

Hypoxia (FiO2 until SpO2 70%)
Pre/Post Pre Post Pre Post Pre Post Pre Post
Variable SpO2 (%) SpO2 (%) MAP (mm Hg) MAP (mm Hg) ETCO2 (mm Hg) ETCO2 (mm Hg) HR (Hz) HR (Hz)
Value 99.3 70.0 95.1 65.2 45.9 41.3 5.7 5.8
95% CI 98–100 70–70 88–102 58–72 44–47 40–43 5.5–6.0 5.6–6.1
% change −29* −32* −10* 2
95% CI −30 to −29 −37 to −25 −13 to −7.6 0.23 to 4.1
Cyanide Injection (5 mg/kg NaCN IV)
Pre/Post Pre Post Pre Post Pre Post Pre Post
Variable SpO2 (%) SpO2 (%) MAP (mm Hg) MAP (mm Hg) ETCO2 (mm Hg) ETCO2 (mm Hg) HR (Hz) HR (Hz)
Value 98.5 97.0 95.1 37.1 45.0 30.0 5.8 3.0
95% CI 97–100 94–100 89–102 32–42 13–47 27–32 5.6–6.1 2.6–3.3
% change −2 −61* −33* −48*
95% CI −4.7 to 1.7 −65 to −56 −38 to −28 −56 to −41
*

Denotes p < 0.05