Figure 9. Three-dimensional (3D) illustration of the small molecule interaction in the ACE2 binding site of the receptor-binding domain of SARS-CoV-2-S.
A) Interaction of streptomycin facilitated by five H-bonds. B) Interaction of ciprofloxicine facilitated by two H-bonds. C) Interaction of glycyrrhizic acid facilitated by five H-bonds. This figure was generated using Schrodinger’s Maestro visualizer. As an alternative, the open source visualizer Python Molecule Viewer (PMV) 48 could also be used.