Table 3.

Effects of active ingredients in Chinese herbal medicines in AAA inanimal models

Active ingredients of Chinese herbal medicines	Working mechanism	References
Ginsenoside Rb1	Produced by MMP, degrading ECM, inflammatory cell infiltration, VSMC dysfunction, inhibiting the JNK and p38 signaling pathways	[63]
Aalvianolic acid C and A	Inhibiting the activity of MMP-2 and MMP-9, inhibiting macrophage infiltration, protecting elastin	[64, 65]
EGCG-3"-O-Me. (green tea polyphenols)	Inhibiting the MMP-9 expression and MMP-1 activity	[66]
Quercetin	Inhibiting MMP-2 and MMP-9 activities	[67]
Ginkgo leaf extract	Inhibiting the activity of MMP-2 and MMP-9, protecting elastin	[68]
Baicalein	Inhibiting MMP-2 and MMP-9 activities	[69]
Resveratrol	Inhibiting MMP-2 and MMP-9 activities	[70]
Ursolic acid	Inhibiting the expressions of MMP-2, MMP-9 and ADAM18, protecting elastin	[71]
Daidzein	Inhibiting MMP-2 and TIMP-1	[72]