Table 1.
Summary of different clusters of gene responses
| Differentially expressed | Down-regulated | Up-regulated | Total regulated | Down-regulated | Up-regulated | Total regulated | |
|---|---|---|---|---|---|---|---|
| % | (p-value < 0.05; |log2FC| | > 1) | (p-value < 0.05; |log2FC| > 2) | |||||
| CBP vs. Solo (h) | |||||||
| 24 | 5.8 | 207 | 114 | 321 (1.2%) | 49 | 26 | 75 (0.3%) |
| 48 | 14.6 | 302 | 343 | 645 (2.5%) | 70 | 109 | 179 (0.7%) |
| 96 | 15.1 | 513 | 253 | 766 (3.0%) | 148 | 72 | 210 (0.8%) |
| CHP vs. SOLO (h) | |||||||
| 24 | 20.4 | 414 | 534 | 948 (3.7%) | 41 | 199 | 240 (0.9%) |
| 48 | 16.1 | 297 | 561 | 858 (3.3%) | 54 | 188 | 242 (0.9%) |
| 96 | 18.7 | 644 | 591 | 1235 (4.8%) | 114 | 260 | 374 (1.5%) |
The percentage of differentially expressed transcripts (p < 0.05) is shown in the second column for every condition and is depicted as a percentage of the total number (i.e. 25 684) of mapped genes. Column 3 and 4 show differentially expressed transcripts in cocultured vs. solocultured endothelial cells characterized by a |log2FC| > 1. Column 6 and 7 depict differentially expressed transcripts characterized by a |log2FC| > 2