Fig. 2. NgBR regulates EMT in NSCLC cell lines.
A, expression of NgBR, E-cadherin, and Vimentin in NSCLC cells using Western blot analysis. β-actin was used as a loading control. B, A549 cells were transfected with plRES-NgBR (NgBR) or plRES-NC (NC) for 72 h and subjected to Western blot analysis of different proteins. C, H1299 cells were transfected with NgBR siRNAs (SI, S2, and S3) or All-Star non-silencing siRNA (NS) for 72 h and then subjected to whole-cell lysate extraction and Western blot analysis. D and E, A549 cells were stably transfected with plRES-NC (NC) or plRES-NgBR (NgBR), while HI299 cells were stably transfected with NgBR shRNA (shNgBR) or nonspecific control (NC) and then subjected to Western blot analysis.