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The effect of various concentrations of 3D sodium alginate scaffolds (0.25%, 0.5%, and 1%) and 2D medium (control) on the percentage of antrum formation (A) and the percentage of degenerated follicles (B). The major percentage of antrum formation is related to the concentration of 0.5% and the maximum count of degenerative follicles is related to the 2D medium. *: Significant difference with the control group (p = 0.00).
