Table 2.

Liver to body weight ratio, plasma osmolality, and hematocrit in sham-ligated rats injected with the control vector (Sham SCR), sham rats injected with shRNA against BDNF (Sham shBDNF), bile duct ligated rats injected with control vector (BDL SCR), and bile duct ligated rats injected with shRNA against BDNF (BDL shBDNF) groups

	Sham SCR	Sham shBDNF	BDL SCR	BDL shBDNF
Liver Wt/body Wt	0.052±0.001 (6)	0.048±0.003 (9)	0.086±0.002 (6)*	0.086±0.002 (8)*
Osmolality, mOsm/kg	299.9±0.94 (6)	301.4±1.11 (9)	289.4±0.72 (6)*	295.5±0.53 (6)*, +
Hematocrit, %	45.4±0.53 (6)	45.5±0.44 (8)	39.1±1.09 (6)*	42.9±0.45 (6)+

Values are mean ± SEM; n, number of rats in each group, in parenthesis. SCR, scrambled; shBDNF, shRNA against BDNF; BDL, bile duct ligated; BDNF, brain-derived neurotrophic factor.

^*p < 0.05 versus control groups (liver to body wt: F[3,25] = 59.304; osmolality: F[3,23] = 32.115; hematocrit: F[3,22] = 20.771).

⁺p < 0.05 versus BDL SCR.