Table 1.

Studies Suggesting Redox of Nitroxides by Oxidative Species

Source of Oxidative Stress (OS Group)	Treatment to Reduce Oxidative Stress (Antioxidant Group)	Nitroxide	Referi
Hyperoxia	Glutathione, uric acid	3-CP	[59]
Asbestosis	Lactate dehydrogenase, catalase N-acetyl-b-D-glucoaminidase (NAG).*	Tempol	[38]
Diabetes (induced by streptozotocin)	Insulin, alpha-tocopherol, SOD	3-CP	[45]
X-ray radiation	Cysteamine	3-CP	[49]
Ultraviolet radiation	Topical sunscreen, topical antioxidants	3-CxP	[47,48]
Brain ischemia-reperfusion	MCI-186	3-CP	[42]
Brain ischemia-reperfusion	Trolox	M-CP	[44]

^*These antioxidants were not administered; their levels increased with the onset of asbestosis.