Table 1.
Clinical characteristics of 150 bacterial CAP patients (non-survivors n = 75 vs. survivors n = 75) and in-hospital death cohort (n = 26)
| Variables | Survivors (n = 75) | Non-survivors (n = 75) | In-hospital death (n = 26) |
|---|---|---|---|
| Age years (mean ± SD) | 78.6 ± 8.8 | 78 ± 8.7 | 76.7 ± 10.5 |
| Male/female | 31/44 | 31/44 | 7/19 |
| Weight (mean ± SD) | 158 ± 36.8 | 147.5 ± 42.3 | 145.63 ± 50.4 |
| Hospital LOS | 7.17 ± 4.1 | 9.85 ± 7.4 | 11.1 ± 11.4Ŧ |
| ICU LOS | 0.76 ± 2.3 | 1.97 ± 3.3 | 3.9 ± 4Ŧ |
| APACHE III | 60.4 ± 15.2 | 73.7 ± 20.6* | 82.9 ± 24.4Ŧ |
| PSI (day 0) | 77.2 ± 5.7 | 97.8 ± 51.7* | 121 ± 46.9 |
| PSI (day 1) | 112.4 ± 31.4 | 134.5 ± 38.7* | 157.8 ± 41.7Ŧ |
| PSI (day 1 no age) | 38.2 ± 26.9 | 60 ± 38* | 84.0 ± 41.0Ŧ |
| Mechanical ventilationa | 4 (5.3) | 20 (26.6)* | 15 (57.6)Ŧ |
| Noninvasive ventilationa | 5 (6.6) | 12 (16)* | 3 (11.5) |
| Comorbiditiesa | |||
| Other respiratory diseases | 25 (35) | 33 (44) | 9 (34) |
| Neoplastic diseases | 4 (5) | 7 (9) | 3 (11) |
| Neurological diseases | 10 (7) | 17 (22)* | 2 (8) |
| Aids | 0 (0) | 1 (1.3) | 1 (4) |
| Sepsis | 19 (32) | 30 (47) | 14 (53)Ŧ |
| Liver disease | 0 (0) | 1 (1.6) | 1 (4) |
| CHF | 19 (33) | 15 (24) | 6 (25) |
| Cerebrovascular disease | 10 (5) | 10 (6)* | 1 (4) |
| Renal disease | 3 (5.7) | 7 (11) | 3 (12)Ŧ |
| Altered mental status | 6 (10.5) | 11 (18)* | 8 (33)Ŧ |
| Smoker | 50 (66) | 51 (68) | 19 (73) |
| Alcoholism | 22 (29) | 16 (21) | 5 (19) |
| Pregnancy | 21 (16) | 10 (13) | 1 (4) |
| Clinical manifestationa | |||
| Lowest temperature (°C) | 36.43 ± 0.58 | 36.46 ± 2.1 | 36.39 ± 2.5 |
| Highest temperature (°C) | 37.20 ± 0.68 | 37.27 ± 0.88 | 37.15 ± 0.81 |
| Pulse ≥ 125/min | 6 (8) | 12 (16) | 6 (23) |
| BUN ≥ 30 mg/dl | 12 (16) | 27 (36)* | 15 (57)Ŧ |
| Respiratory rate/min | 9 (15) | 17 (27) | 9 (34)Ŧ |
| PO2 < 60 mm/Hg | 21 (36) | 24 (44) | 13 (50) |
| pH < 7.35 | 3 (4) | 4 (6)* | 4 (15) |
| Lowest systolic BP (mm/Hg) | 118 ± 19 | 116 ± 24 | 115 ± 21 |
| Highest systolic BP (mm/Hg) | 146 ± 22 | 148 ± 25 | 149 ± 23 |
| Highest creatinine (mg/dl) | 1.27 ± 0.79 | 1.92 ± 1.59 | 1.95 ± 1.52 |
SD standard deviation, LOS length of stay, APACHE III Acute Physiology and Chronic Health Evaluation used as an ICU scoring system, PSI Pneumonia Severity Index, CHF Congestive Heart Failure. aData is no. (%) of subjects, unless otherwise indicated; *significant difference between non-survivors and survivors; Ŧsignificant difference between in-hospital death cases and survivors