Table 9.

Infertility risk factors: Results of the bivariate and multivariate logistic regression analysis, Women Hospital-Hamad Medical Corporation, 2018

Independent risk factors	Crude Odd ratio (cOR)	95% Confidence interval (CI)	Adjusted Odd ratio (aOR)	p-value	95% Confidence interval (CI)
Model I: Independent risk factors of infertility^a
Age of participants (> 35 y)	2.31	1.24–4.29	3.72	0.008*	1.41–9.83
Second hand smoking	1.78	1.18–2.70	2.44	0.008*	1.26–4.73
Steady weight gain since marriage	8.17	5.11–13.05	4.65	0.001*	2.43–8.91
Recent weight gain	9.08	5.62–14.69	4.87	0.001*	2.54–9.32
Menstrual cycle irregularity	6.43	3.44–12.04	4.20	0.031*	1.14–15.49
Sexually transmitted infections (STIs) suggestive symptoms:
Lower abdominal/pelvic pain	10.82	3.95–19.67	3.46	0.002*	1.57–7.63
Abnormal vaginal discharge	8.54	4.19–17.44	3.32	0.019*	1.22–9.03
Dyspareunia	18.44	8.95–37.60	7.04	0.001*	2.76–17.95
Fallopian tube blockage	7.71	3.22–18.47	5.45	0.003*	1.75–16.95
Model II: Independent risk factors of secondary infertility^b
Time from last conception ≥ 5y	4.9	2.78–8.65	5.8	0.001*	3.28–10.21
History of stillbirth (once or more)	3.24	1.39–7.52	2.63	0.042*	1.04–6.67
Miscarriage (once or more)	1.94	1.18–3.17	2.11	0.008*	1.21–3.68
Post-partum / Post-abortal infection	3.84	1.42–10.42	3.75	0.016*	1.27–11.06

* p < 0.05

^a Model I: X² (12) = 264, p < 0.001, Nagelkerke R² = 0.661

^b Model II: X² (4) = 57.3, p < 0.001, Nagelkerke R² = 0.233

Model I included comparison between total cases (n = 136) and total controls (n = 272)

Model II included comparison between secondary infertile women (n = 93) and only controls who reported previous conception (n = 230)