Table 2.
Baseline characteristics and outcomes of PGT-SR cycle.
| Characteristics | EFLL (n = 37) | MLSL (n = 148) | P-value |
|---|---|---|---|
| Classification | |||
| Robertsonian translocation | 18.9% (7/37) | 16.2% (24/148) | |
| Reciprocal translocation | 59.5% (22/37) | 73.6% (109/148) | |
| Inversion | 21.6% (8/37) | 10.1% (15/148) | |
| Age (years) | 29.78 ± 4.95 | 29.64 ± 5.16 | NS |
| BMI (kg/m2) | 22.19 ± 2.26 | 22.14 ± 2.14 | NS |
| AFC | 15.46 ± 6.56 | 15.18 ± 6.62 | NS |
| bFSH (IU/L) | 6.13 ± 1.87 | 6.50 ± 1.92 | NS |
| bE2 (pg/mL) | 37.96 ± 25.64 | 45.30 ± 52.67 | NS |
| bLH (IU/L) | 4.77 ± 2.55 | 5.35 ± 3.15 | NS |
| Gn days | 12.43 ± 2.50 | 10.87 ± 1.51 | 0.001 |
| Total dosage of Gn (IU) | 2,351.69 ± 1,003.72 | 2,218.07 ± 822.70 | NS |
| Endometria thickness on hCG day (mm) | 12.22 ± 2.57 | 11.30 ± 2.56 | NS |
| LH on hCG day (IU/L) | 0.69 ± 0.47 | 1.55 ± 0.93 | <0.001 |
| E2 on hCG day (pg/mL) | 5,415.65 ± 2,849.30 | 5,650.79 ± 3,432.62 | NS |
| No. of retrieved oocytes | 19.35 ± 9.01 | 16.61 ± 8.79 | NS |
| E2/no. of retrieved oocytes | 283.78 ± 126.87 | 377.20 ± 259.45 | 0.035 |
| MII oocytes rate (%) | 80.9% (579/716) | 82.4% (2,026/2,458) | NS |
| Fertilization rate (%) | 81.2% (470/579) | 76.6% (1,551/2,026) | 0.019 |
| No. of biopsied blastocysts | 5.89 ± 3.96 | 4.80 ± 3.26 | NS |
| No. of euploid embryos | 1.76 ± 1.54 | 1.21 ± 1.24 | 0.024 |
| Euploidy rate (%) | 31.9% (65/204) | 25.7% (179/696) | NS |
BMI, body mass index; AFC, antral follicle count; Gn, gonadotropin; hCG, human chorionic gonadotrophin.
Data are presented as mean ± SD or % (no./total no.).