Table 1.
Features of pogo transposase domesticated proteins identified in vertebrate
| Group | Gene | Protein length (aa) | Sequence identity (Species number) | Ka / Ks ratio (Species number / Z-test) | Conserved domains | |||
|---|---|---|---|---|---|---|---|---|
| DBD domain | DDE domain | Catalytic triad | Additional functional domains | |||||
| Tigger-derived | TIGD2 | ~ 525 | 91.62 ± 0.05 (n = 121) | 0.093 ± 0.029 (n = 120 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD34S | |
| JRKL | ~ 524 | 92.93 ± 0.08 (n = 121) | 0.055 ± 0.022 (n = 117 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD34D/N | ||
| JRK | ~ 530–570 | 74.60 ± 0.10 (n = 118) | 0.207 ± 0.073 (n = 114 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD32D/E | ||
| TIGD5 | ~ 530–670 | 74.13 ± 0.10 (n = 165) | 0.176 ± 0.099 (n = 161 / P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | ? | ||
| TIGD7 | ~ 550 | 87.45 ± 0.10 (n = 91) | 0.171 ± 0.066 (n = 87 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD34N | ||
| CENPBD1 | ~ 540 | 79.50 ± 0.36 (n = 63) | 0.177 ± 0.098 (n = 62 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD32G | ||
| pogoR-derived | CENPB | ~ 600 | 89.80 ± 0.09 (n = 119) | 0.090 ± 0.062 (n = 115 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | ? | CENP-B_dimeris |
| TIGD6 | ~ 520 | 87.08 ± 0.15 (n = 76) | 0.207 ± 0.140 (n = 76 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | DD30N | ||
| TIGD3 | ~ 470 | 80.63 ± 0.11 (n = 124) | 0.195 ± 0.069 (n = 123 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | ? | ||
| TIGD4 | ~ 510 | 77.74 ± 0.08 (n = 188) | 0.142 ± 0.050 (n = 186 /P < 0.05) | CENP-B_N/HTH_Tnp_Tc5 | DDE_1 | ? | ||
| Passer-derived | POGK | ~ 610 | 90.75 ± 0.08 (n = 122) | 0.062 ± 0.043 (n = 117 /P < 0.05) | BrkDBD/HTH_Tnp_Tc5 | DDE_1 | DN35D | KRAB |
| POGZ | ~ 1200–1410 | 83.63 ± 0.08 (n = 204) | 0.068 ± 0.048 (n = 198 /P < 0.05) | HTH_Tnp_Tc5 | DDE_1 | DD35D | ZNF | |