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. 2020 Jul 20;40(7):942–948. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.07.05

2.

骨膜素对缺氧诱导的人牙周膜成纤维细胞凋亡的影响

Effect of periostin on apoptosis of hypoxia-induced human periodontal ligament fibroblasts (Mean±SD, n=9)

Group Bcl-2 Bax Cleaved caspase-3 Cell apoptosis rate (%)
*P < 0.05, compare with 0 ng/mL; #P < 0.05 compare with hypoxia group.
Control 0.73±0.06 0.26±0.05 0.34±0.04 3.28±0.47
Hypoxia 0.24±0.05* 1.14±0.12* 0.83±0.08* 21.24±2.37*
Hypoxia+25 ng/mL 0.37±0.06# 0.73±0.07# 0.59±0.07# 14.37±1.58#
Hypoxia+50 ng/mL 0.44±0.05# 0.61±0.06# 0.42±0.06# 11.98±1.26#
Hypoxia+100 ng/mL 0.69±0.08# 0.45±0.05# 0.33±0.05# 10.72±1.52#
F 107.008 177.210 105.324 154.663
P 0.000 0.000 0.000 0.000