2.
骨膜素对缺氧诱导的人牙周膜成纤维细胞凋亡的影响
Effect of periostin on apoptosis of hypoxia-induced human periodontal ligament fibroblasts (Mean±SD, n=9)
Group | Bcl-2 | Bax | Cleaved caspase-3 | Cell apoptosis rate (%) |
*P < 0.05, compare with 0 ng/mL; #P < 0.05 compare with hypoxia group. | ||||
Control | 0.73±0.06 | 0.26±0.05 | 0.34±0.04 | 3.28±0.47 |
Hypoxia | 0.24±0.05* | 1.14±0.12* | 0.83±0.08* | 21.24±2.37* |
Hypoxia+25 ng/mL | 0.37±0.06# | 0.73±0.07# | 0.59±0.07# | 14.37±1.58# |
Hypoxia+50 ng/mL | 0.44±0.05# | 0.61±0.06# | 0.42±0.06# | 11.98±1.26# |
Hypoxia+100 ng/mL | 0.69±0.08# | 0.45±0.05# | 0.33±0.05# | 10.72±1.52# |
F | 107.008 | 177.210 | 105.324 | 154.663 |
P | 0.000 | 0.000 | 0.000 | 0.000 |