. 2020 Jul 20;40(7):942–948. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.07.05

4.

骨膜素对缺氧诱导的人牙周膜成纤维细胞IL-1β、IL-6和TNF-α分泌的影响

Effect of periostin on IL-1β, IL-6 and TNF-α expression of hypoxia-induced human periodontal ligament fibroblasts (Mean±SD, n=9)

Group	IL-1β（ng/L）	IL-6（ng/L）	TNF-α（ng/L）
^*P < 0.05, compare with 0 ng/mL; ^#P < 0.05 compare with hypoxia group.
Control	22.51±2.42	82.21±7.24	133.85±15.63
Hypoxia	74.14±6.43^*	264.35±13.29^*	444.57±36.37^*
Hypoxia+25 ng/mL	58.16±5.61^#	208.49±15.11^#	375.65±29.85^#
Hypoxia+50 ng/mL	45.06±4.77^#	175.65±15.88^#	291.52±17.92^#
Hypoxia+100 ng/mL	38.60±3.30^#	158.57±13.25^#	252.43±16.70^#
F	153.464	228.086	208.082
P	0.000	0.000	0.000