4.
不同聚类的临床特征
Clinical features of different clusters of patients
| Factors | Cluster 1 | Cluster 2 | Cluster 3 | Test statistics | P |
| Note: Qualitative variables were presented as counts (n) and percentages (%) and were compared between groups using Fisher's exact test. Quantitative variables were presented as Means ± SD and were compared using the one-way analysis of variance (ANOVA). NA: Not applicable. | |||||
| Male/female | 14/15 | 4/3 | 10/25 | NA | 0.171 |
| Age (year) | 49±13 | 49±8 | 51±10 | 0.256 | 0.775 |
| Rash | 28 (96.5) | 2 (28.5) | 7 (20.0) | NA | < 0.001 |
| Raynaud | 0 | 1 (14.2) | 1 (2.8) | NA | 0.189 |
| Arthralgia | 8 (27.5) | 1 (14.2) | 9 (25.7) | NA | 0.926 |
| Mechanic hands | 3 (10.3) | 0 | 3 (8.5) | NA | 1 |
| Dysphagia | 7 (24.1) | 0 | 4 (11.4) | NA | 0.260 |
| Myalgia | 11 (37.9) | 3 (42.8) | 11 (31.4) | NA | 0.766 |
| Amyasthenia | 14 (48.2) | 6 (85.7) | 18 (51.4) | NA | 0.226 |
| ILD | 17 (58.6) | 3 (42.8) | 25 (71.4) | NA | 0.260 |
| Malignancy | 4 (13.7) | 0 | 5 (14.2) | NA | 0.016 |
| Infection | 7 (24.1) | 3 (42.8) | 14 (40.0) | NA | 0.334 |
| Albuminuria | 9 (31.0) | 1 (14.2) | 9 (25.7) | NA | 0.794 |
| CRP (mg/L） | 21.3±33.0 | 12.8±21.7 | 15.9±43.0 | 0.234 | 0.792 |
| ESR (mm/h） | 40.0±31.5 | 39.3±25.8 | 35.5±32.0 | 0.168 | 0.846 |
| Glb (g/L) | 30.0±6.2 | 27.8±3.2 | 32.5±7.1 | 2.18 | 0.121 |
| Alb (g/L) | 30.5±5.0 | 34.0±4.7 | 35.4±5.8 | 6.5 | 0.003 |
| CK (U/L) | 1558±2739 | 5734±3996 | 1575±1921 | 8.64 | < 0.001 |
| CK-MB (U/L) | 92±179 | 318±406 | 56±78 | 6.53 | 0.003 |
| LDH (U/L) | 616±564 | 836±721 | 390±239 | 3.78 | 0.028 |
| α-HBDH (U/L) | 451±379 | 642±592 | 287±178 | 4.35 | 0.017 |
| AST (U/L) | 132±168 | 155±146 | 64±64 | 3.09 | 0.052 |
| ALT (U/L) | 75±92 | 117±116 | 62±58 | 1.43 | 0.247 |