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. 2020 Jul 9;16:62. doi: 10.1186/s13223-020-00460-y

Table 2.

Significant associations between SNVs in VDR gene with atopy, asthma symptoms and asthma severity

Phenotype SNVs Alele Model ORa CI 95% p valueb
Atopyc
 VDR rs10875694 A ADD 1.35 1.01–1.81 0.043
Asthma symptoms
 VDR rs9729 C ADD 0.66 0.45–0.97 0.033
Severe asthma
 VDR rs2189480 A ADD 0.34 0.13–0.89 0.029
rs4328262 G ADD 3.18 1.09–9.28 0.034

aUsing logistic regression adjusted by sex, age, and individual genetic ancestry

bPermutational analysis

csIgE ≥ 0.70 to common aeroallergens; ADD additive analysis model