Table 1.

Clinical and laboratory characteristics of subjects in two group

Variable	Patients (n = 30)	Controls (n = 30)	P value
Age, median (IQR), years	7.5 (5–9.25)	7 (5.75–11)	0.77
Sex, male/female	17/13	14/16	0.606
Allergen (positive/negative)	21/9	6/24	< 0.001
Eosinophils in blood, average (95% CI)	2.97 (2.662–3.285)	2.207 (2.032–2.381)	< 0.001
FEV1.0/FVC%	75.3 ± 12.03	91.2% ± 8.76	< 0.001
IDO in sputum, average (95% CI)	5.442 (4.950–5.935)	8.912 (8.398–9.426)	< 0.001
IDO in blood, average (95% CI)	3.136 (2.787–3.485)	4.12 (3.638–4.603)	0.001
Treg, average ± SD (%)	3.97 ± 2.052	5.69 ± 2.434	< 0.01
Th17/Treg, average ± SD	0.45 ± 0.430	1.04 ± 0.666	0.002

IDO unit: %; Eosinophils unit: %

IDO indoleamine 2,3-dioxygenase, FEV1.0/FVC% maximum expiratory rate in the first second, IQR interquartile range, CI confidence interval