Table 2.
Proteins in the SARS CoV-2, their names and brief description of their function.
| No. | Protein | Description |
|---|---|---|
| 1 | nsp1 | Suppresses host antiviral response |
| 2 | nsp2 | |
| 3 | nsp3 | nsp3–nsp4–nsp6 complex involved in viral replication |
| 4 | nsp4 | nsp3–nsp4–nsp6 complex involved in viral replication |
| 5 | nsp5 | Main protease (3C-like) |
| 6 | nsp6 | nsp3–nsp4–nsp6 complex involved in viral replication |
| 7 | nsp7 | nsp7–nsp8 complex is part of RNA polymerase |
| 8 | nsp8 | nsp7–nsp8 complex is part of RNA polymerase |
| 9 | nsp9 | ssRNA binding |
| 10 | nsp10 | Essential for nsp16 methyltransferase activity |
| 11 | nsp11 | Short peptide |
| 12 | nsp12 | RNA polymerase |
| 13 | nsp13 | Helicase/triphosphatase |
| 14 | nsp14 | 3’–5’ exonuclease |
| 15 | nsp15 | Uridine-specific endoribonuclease |
| 16 | nsp16 | RNA-cap methyltransferase |
| 17 | S | Spike protein, mediates binding to ACE2 |
| 18 | Orf3a | Activates the NLRP3 inflammasome |
| 19 | Orf3b | |
| 20 | E | Envelope protein, involved in virus morphogenesis and assembly |
| 21 | M | Membrane glycoprotein, predominant component of the envelope |
| 22 | Orf6 | Type I IFN antagonist |
| 23 | Orf7a | Virus-induced apoptosis |
| 24 | Orf7b | |
| 25 | Orf8 | |
| 26 | N | Nucleocapsid phosphoprotein, binds to RNA genome |
| 27 | Orf9b | Type I IFN antagonist |
| 28 | Orf9c | |
| 29 | Orf10 |