Table 3.
Prevalence rate for β-thalassemia and Sickle Cell disorders by region, in Saudi Arabia, 2011–2015.
β-thalassemia | Sickle Cell Disorder | ||||||||
---|---|---|---|---|---|---|---|---|---|
Regions | Population | Trait | 95%CI | Disease* | 95%CI | Carrier | 95%CI | Disease* | 95%CI |
Al-Baha | 29,161 | 13.2 | 11.9–14.6 | 0.3 | 0.2–0.6 | 34.9 | 32.8–37.0 | 2.8 | 2.2–3.5 |
Al-Jouf | 29,339 | 2.9 | 2.3–3.5 | 0.3 | 0.1–0.5 | 2.6 | 2.0–3.2 | 1 | 0.7–1.4 |
Asir | 1,65,316 | 6.7 | 6.3–7.1 | 0.2 | 0.1–0.2 | 42.5 | 41.5–43.4 | 7 | 6.6–7.4 |
Eastern Region | 2,11,727 | 23.7 | 23.1–24.4 | 0.4 | 0.3–0.5 | 114.4 | 113.0–115.8 | 9.8 | 9.4–10.2 |
Hail | 38,567 | 3.3 | 2.8–3.9 | 0.00 | 0.0–0.1 | 2.0 | 1.6–2.5 | 0.1 | 0.0–0.2 |
Jazan | 72,420 | 32.1 | 30.8–33.4 | 0.6 | 0.5–0.8 | 135.7 | 133.2–138.2 | 6.8 | 6.2–7.4 |
Makkah | 2,38,978 | 14.4 | 13.9–14.9 | 1.9 | 1.7–2.1 | 31.3 | 30.6–32 | 1.9 | 1.7–2.1 |
Maddinah | 81,286 | 8.1 | 7.55–8.79 | 0.2 | 0.1–0.3 | 13.7 | 13–14.6 | 0.8 | 0.6–0.9 |
Najran | 24,836 | 2.4 | 1.9–3.1 | 0.00 | 0.0–0.2 | 12.6 | 11.3–14.1 | 0.3 | 0.2–0.6 |
North Border | 22,260 | 7.6 | 6.5–8.8 | 3.4 | 2.7–4.3 | 4.0 | 3.3–5 | 0.4 | 0.2–0.8 |
Qasim | 70,057 | 4.0 | 3.6–4.5 | 0.4 | 0.3–0.6 | 2.5 | 2.2–2.9 | 0.3 | 0.2–0.5 |
Riyadh | 2,00,652 | 7 | 6.6–7.4 | 0.2 | 0.2–0.3 | 18.1 | 17.6–18.7 | 1.1 | 0.9–1.2 |
Tabouk | 45,983 | 6.3 | 5.6–7.1 | 0.2 | 0.1–0.4 | 27.5 | 26.0–29.0 | 1.0 | 0.8–1.4 |
95%CI = 95% confident interval.
[3] Memish ZA, Owaidah TM, Saeedi MY. Marked regional variations in the prevalence of sickle cell disease and beta-thalassemia in Saudi Arabia: findings from the premarital screening and genetic counseling program. J Epidemiol Global Health 2011;1(1):61–68. doi: 10.1016/j.jegh.2011.06.002. PubMed PMID: 23856375.
Significant presentation among the B-thalassemia and Sickle cell disease p-value = 0.0001 [3].