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. 2020 Jul 28;182(6):1560–1573.e13. doi: 10.1016/j.cell.2020.07.033

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Figure S3 — Cryo-EM Processing Pipeline and Analysis for the nsp13-RTC (No Detergent) Dataset, Related to Figure 2

A. Cryo-EM processing pipeline.

B. Nominal 3.6 Å-resolution cryo-EM reconstruction of nsp13₂-RTC (no detergent) filtered by local resolution (Cardone et al., 2013) and colored by subunit according to the key on the right.

C. Directional 3D Fourier shell correlation (FSC) for nsp13₂-RTC (no detergent) calculated by 3DFSC (Tan et al., 2017).

D. Angular distribution plot for reported nsp13₂-RTC (no detergent) calculated in cryoSPARC. Scale shows the number of particles assigned to a particular angular bin. Blue, a low number of particles; red, a high number of particles.

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