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Examples Of Vaccine Strategies For SARS CoV Adapted from Enjuanes et al., Gillim-Ross et al., Lin et al.60 and Martin et al.61
| Vaccine type | Animal studies | Induction of neutralizing antibodies/protection | Human trials |
|---|---|---|---|
| Inactivated virus | Mice | + | + |
| Subunit or expressed protein | Mice | + | − |
| Viral or bacterial expression vectors (S or N protein) | Mice, ferrets, primates | + | − |
| DNA vaccine (S, N, M protein) | Mice, primates | + | + |
| Live attenuated virus | Hamsters | + | − |
