Table 1.
Changes in Performance-based Measures and Patient-reported Outcomes
| PRT (n = 35) | FLEX (n = 35) | Between group Δ | |||
|---|---|---|---|---|---|
| Baseline | Δ | Δ | p-value* | ||
| Performance Based Measures | |||||
| SPPB (0-12) | 7.6 (1.4) | 1.6 (2.0) | 7.3 (1.7) | 1.9 (2.0) | 0.58 |
| Balance score | 2.6 (1.1) | 0.3 (1.4) | 2.5 (1.3) | 0.7 (13) | 0.23 |
| Chair stand time (s) | 16.0 (5.1) | −3.9 (5.3) | 16.7 (4.7) | −2.5 (3.4) | 0.23 |
| 4-meter walk time (s) | 5.4 (0.9) | −0.7 (0.8) | 5.3 (1.0) | −0.5 (0.9) | 0.34 |
| Stair Climb (s) | 6.8 (1.8) | −0.4 (1.1) | 6.9 (2.4) | −0.1 (1.8) | 0.39 |
| 6 Minute Walk Distance (m) | 375 (58.6) | 29.6 (44.7) | 377 (62.0) | 25.3 (59.6) | 0.75 |
| Patient Reported Outcomes | |||||
| Pittsburgh Fatigability Scale | |||||
| Activity Participation | 5.4 (1.9) | 1.1 (1.6) | 5.4 (2.0) | 0.2 (1.4) | 0.03 |
| Physical | 21.0 (9.0) | −2.5 (7.9) | 21.8 (9.8) | −2.1 (6.5) | 0.81 |
| Mental | 12.0 (10.5) | −1.6 (9.2) | 15.6 (10.1) | 0.7 (8.6) | 0.30 |
| Late Life Functioning and Disability Index | |||||
| Difficulty performing activities | 123 (18.6) | 4.3 (10.2) | 123 (22.0) | −0.03 (11.4) | 0.11 |
| Limited doing activities | 67.7 (9.6) | 3.9 (75) | 64.2 (11.2) | 2.2 (7.4) | 0.33 |
| Frequency of activities | 57.1 (7.0) | 2.3 (3.9) | 55.8 (7.7) | 0.7 (4.0) | 0.12 |
| Basic lower extremity raw score | 59.3 (8.0) | 1.3 (4.6) | 58.8 (9.4) | 0.5 (5.1) | 0.47 |
| Advanced lower extremity raw score | 33.3 (9.4) | 2.3 (5.0) | 34.6 (10.4) | −0.7 (5.0) | 0.02 |
| Age-Related Muscle Loss Questionnaire | 37.2 (27.8) | −10.0 (19.7) | 35.5 (28.0) | −3.3 (15.0) | 0.12 |
*
P-value calculated from a linear regression model adjusting for sex; Results are means (SD), unless otherwise stated. Changes calculated as 12-week minus baseline value. MMSE, Mini-Mental State Exam; SPPB, Short physical performance battery.