Table 3.
Correlations Between Changes in Performance-Based and Patient-Reported Functional Outcomes and Muscle Torque Capacity
| Baseline Torque Capacity | Change in Torque Capacity | |||
|---|---|---|---|---|
| r | p-value | r | p-value | |
| Performance Based Measures | ||||
| Total SPPB Score | −0.13 | 0.34 | 0.32 | 0.01 |
| Balance Score | −0.20 | 0.12 | 0.33 | 0.01 |
| Chair stand time | 0.02 | 0.90 | −0.25 | 0.07 |
| Walk time | 0.11 | 0.41 | −0.16 | 0.21 |
| Stair climb time | 0.39 | <0.01 | −0.12 | 0.37 |
| 6MW distance | 0.02 | 0.90 | 0.08 | 0.54 |
| Patient Reported Outcomes | ||||
| Pittsburgh Fatigability Scale | ||||
| Activity Participation | 0.09 | 0.50 | 0.38 | <0.01 |
| Mental | −0.07 | 0.60 | −0.17 | 0.22 |
| Physical | 0.17 | 0.21 | −0.15 | 0.26 |
| Late Life Function and Disability Instrument | ||||
| Difficulty with activities | −0.13 | 0.31 | 0.20 | 0.13 |
| Limited doing activities | −0.13 | 0.33 | 0.44 | <0.01 |
| Frequency of activities | 0.02 | 0.89 | 0.32 | 0.01 |
| Basic lower extremity score | −0.19 | 0.15 | 0.19 | 0.15 |
| Advanced lower extremity | −0.19 | 0.15 | 0.24 | 0.07 |
| Aging Muscle Loss Questionnaire | 0.29 | 0.03 | −0.06 | 0.64 |
Changes calculated as 12-week minus baseline value. Partial r-values adjusted for age, sex, and BMI. Muscle torque capacity defined as average summed torque from Baseline Visits 1 & 2. SPPB, Short Physical Performance Battery; 6MW, Six Minute Walk.