Table 1.
Patient characteristics. DM= Patients with a diagnosis of Diabetes Mellitus not on metformin. FEV1 = Forced expiratory volume in first second. DLCO = Diffusion capacity of lung to carbon monoxide. Adeno = adenocarcinoma. SqCC = Squamous cell carcinoma. BMI = Body mass index. ASA = American Society for Anesthesiology score.
| Characteristic | Non-diabetic | DM | Metformin | P-Value |
|---|---|---|---|---|
| N | 325 | 35 | 74 | |
| Mean Age | 66 | 69 | 72 | <0.05 |
| Female (%) | 210 (65%) | 23(66%) | 37 (50%) | 0.06 |
| Race | ||||
| White | 295 (91%) | 30 (86%) | 64 (86%) | 0.13 |
| Black | 22 (7%) | 3 (9%) | 10(14%) | |
| Other | 8 (2%) | 2 (6%) | 0 (0%) | |
| FEV1 %pred (mean) | 82% | 83% | 83% | NS |
| DLCO%pred (mean) | 77% | 71% | 78% | NS |
| Tumor grade | ||||
| I/II | 222 (68%) | 21 (60%) | 51 (68%) | 0.59 |
| III/IV | 103 (32%) | 14 (40%) | 23 (32%) | |
| Smoking status | 0.27 | |||
| Current | 92 (28.3%) | 9 (25.7%) | 14 (18.9%) | |
| Former | 132 (40.6%) | 21 (60.0%) | 38 (51.4%) | |
| Never | 27 (8.3%) | 3 (8.6%) | 8 (10.8%) | |
| Quit | 49 (15.1%) | 0 (0%) | 9 (12.2%) | |
| Recent quit | 24 (7.4%) | 2(5.7%) | 5 (6.8%) | |
| Unknown | 1 (0.3%) | |||
| Histology | ||||
| Adeno | 243 (75%) | 23 (66%) | 47 (64%) | 0.1 |
| SqCC | 82 (25%) | 12 (34%) | 27 (36%) | |
| BMI (mean) | 26.9 | 30.3 | 31.4 | <0.05 |
| ASA | ||||
| 2 | 184 (57%) | 11 (31%) | 22 (30%) | <0.01 |
| 3 | 138 (42%) | 24 (69%) | 52 (70%) | |
| 4 | 3 (1%) | 0 (0%) | 0 (0%) | |
| BMI ≥25 | 209 (64%) | 29 (83%) | 66 (89%) | <0.01 |
| BMI ≥30 | 69 (21%) | 15 (43%) | 37 (50%) | <0.01 |