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. 2020 Jul 16;16(7):e1008484. doi: 10.1371/journal.pgen.1008484

Table 3. Activity of HXK2 and variants.


HXK2 Allele
2DG Resistance
% Growth in 0.1% 2DG
Catalytic Activity
nmole/min/A.U.
Invertase Activity
mU/OD
WT HXK2 20 4.317 53
hxk2-WRF 16 3.077 58
hxk2-R423T 61 0.127 45
hxk2-D417G 62 0.558 60
hxk2-WCA 73 0.452 134
hxk2-G55V 81 0.017 416
hxk2Δ 80 0.0 611
hxk2-D211A 81 0.0 1020