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. Author manuscript; available in PMC: 2021 Jan 2.
Published in final edited form as: Nat Methods. 2020 Jul 2;17(7):699–707. doi: 10.1038/s41592-020-0878-9

Table 1.

Estimated accuracy of Ribosolve modelsa

System No. nts Final no. particles used for 3D reconstruction Map resolution (Å) Estimated accuracya (Å)
Tetrahymena ribozyme 388 74,621 6.8 3.9
hc16 product 349 29,191 10. 6.3
hc16 338 21,263 11. 6.2
V. cholerae glycine riboswitch with glycine 231 193,317 5.7 3.9
V. cholerae glycine riboswitch apo 231 230,891 4.8 3.3
F. nucleatum glycine riboswitch with glycine 171 35,578 7.4 3.4
F. nucleatum glycine riboswitch apo 171 20,269 10. 3.5
ATP-TTR-3 with AMP 130 39,136 9.6 3.7
ATP-TTR-3 apo 130 71,045 10. 3.7
SAM-IV riboswitch with SAM 119 225,303 4.8 3.6
SAM-IV riboswitch apo 119 260,244 4.7 3.7
a

Accuracy is estimated from the modeling convergence (accuracy = 0.61 × convergence + 2.4), where convergence is defined as the average pairwise RMSD of the top ten scoring models built into half map 1 vs. models built into half map 2 (see Methods).